European water legislation framework and ecotoxicological potential of diclofenac in the aquatic system of the Rhine
Due to the ever increasing use of pharmaceuticals in human and veterinary medicine, pharmaceutical contamination of aquatic ecosystems is considered an emerging problem (Hejna et al., 2022; Rzymski et al., 2017). Back in 2006, the annual per capita consumption of pharmaceuticals has been estimated to be 15 g on average worldwide and as high as […]