Toxicology & Applied Science

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Toxicology & Applied Science

Toxicology & Applied Science

Tag: Read-across

“Read-across” is a term for applying knowledge or conclusions from one situation to another, often used in risk assessment to predict a substance’s properties by comparing it to similar, well-studied substances. It involves using data and insights from one context to inform a decision or fill a data gap in a different but related context, relying on structural and mechanistic similarities to justify the comparison.

Regulatory framework for identification and characterization of endocrine disrupters

For decades, studies of endocrine disrupters (EDs) have challenged traditional concepts in toxicology, in particular the dogma “the dose makes the poison” as they can have effects at low doses that are not predicted by effects at higher doses. At the beginning of the 90s the term endocrine disruption first appeared in scientific literature and a workshop […]